It's important to teach yourself to feel responsible for random events, because with great responsibility comes great power. That's what my wise Uncle Ben told me right before he died; he might still be alive today if only I'd said rabbit rabbit that year!
This comic references the superstition, which is known to have existed as far back as 1909, of saying "rabbit rabbit" on the first day of a month in order to have good luck.
It also mocks magical thinking.
"Uncle Ben" is a reference to Spider-Man, whose uncle told him that "with great power comes great responsibility".