So It Has Come To This
'Come to what?' 'You. Me. This moment.'
'Come to what?' 'You. Me. This moment.'
The line "it has come to this" is usually seen on the verge of the climactic confrontation between the villain and their arch rival, or when one character has to unleash their utmost ability, etc. Despite its dramatic tone, however, the statement is a content-free tautology, true in all possible scenarios in which time progresses in a forward direction. Accordingly, Cueball is saying it when Megan tells him that they have run out of cat food, a relatively trivial problem that could be solved with a quick trip to the grocery store.
The title text is a follow-up on the comic dialogue. When Megan replies in confusion, "Come to what?" Cueball then uses another instantly-dramatic phrase that keeps his words ambiguous, only leaving her in the dark.
Other comics which advocate using catch-all phrases as standard responses for any comment: