xkcd.WTF!?

Explanation ➲

This is another comic in a series related to the COVID-19 pandemic.

On the day this comic was published, the Centers for Disease Control and Prevention (CDC) released new guidelines relating to COVID-19, lifting many of the existing restrictions for people who have been fully vaccinated for two weeks. Megan, speaking as a CDC spokesperson, is introducing these new guidelines in a video press conference. However, the other participants in the press conference quickly start asking about actions that have little or nothing to do with the vaccine, some of which would be dangerous whether COVID-19 was a risk or not, similarly to 2238: Flu Shot. It's possible that they do not remember life before the pandemic very well, as in 2391: Life Before the Pandemic.

Blondie asks whether it would be okay to visit neighbors and drink milk directly from the carton. In most Western cultures, drinking directly from a container that could be shared with others (such as a milk carton) is considered unsafe, due to the risk of diseases being transmitted, and generally gross, as saliva and other biological material is passed that way. While these risks are arguably worse during the pandemic, it was unacceptable before the pandemic and will presumably be so afterward.

Jill asks whether it would be okay to ride a bike down the stairs of a family member's house, which has a severe risk of injury.

White Hat follows up asking whether he can get a horse, and whether it would help for him and/or the horse to wear masks. This has basically no relation to anything else that was said. In response, Megan gives up trying to answer the increasingly irrelevant questions and ends the call.

In the title text, Randall mentions that when he is fully vaccinated, he will be able to write messages in ALL CAPS. This is generally used to indicate shouting, an activity which could spread COVID-19 and cause infection if done in person.