xkcd.WTF!?

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Morning

I'd press on them to try to unstick them, but I can't reach. Can we try cycling day and night really fast?

Explanation

This comic makes reference to the idea, as presented in the movie The Matrix, that reality is a computer simulation. In LCD screens, especially TFT LCD, a dead pixel is a pixel that does not work properly, usually set as black or as some other color. Megan realizes that the reality is a computer simulation when she sees dead pixels in the sky, indicating that what she sees is an LCD screen.

In the last panel of the comic, there are two red and one green pixel that look exactly like actual dead pixels.

The title text refers to usual techniques for fixing a dead pixel. One way is to apply pressure and release it, which isn't possible for Megan due to the distance of the sky. Another way is to make the area of the screen that the dead pixel is on change colors really quickly, which could happen if the day-night cycle was fast enough.