I THINK EVERYONE INVOLVED HERE IS CUTE.
People show up at protests because they're angry about something and want to use peaceful means or otherwise to effect political change. It's very much a groupthink, "mob" mentality, bringing to mind the credo, "If you're not with us, you're against us."
Hardly anyone goes to a protest because they're happy about the way things are, and thus, someone holding up signs saying how happy he is would, to say the least, be very out of place at a protest,[citation needed] although it's more common than expected.
The title text shows another sign Cueball is carrying (although since it compliments the protesters, he may not get in as much trouble for it). It might be a reference to certain protest topic groups that are known for having some members that do not show up because of the protest topic, but show up because of the girls that will be there. (An example of a protest topic is animal rights.)
The title of the comic refers to the oft-seen protest placard "The end is now," signifying that person's belief that we live in the end times, and it's time to start getting right with (insert religious figure of your choice here).